Forthcoming

Ebinger JE, Joung S, Liu Y, Wu M, Weber B, Claggett B, Botting PG, Sun N, Driver M, Kao YH, Khuu B, Wynter T, Nguyen TT, Alotaibi M, Prostko JC, Frias EC, Stewart JL, Goodridge HS, Chen P, Jordan SC, Jain M, Sharma S, Fert-Bober J, Van Eyk JE, Minissian MB, Arditi M, Melmed GY, Braun JG, McGovern DPB, Cheng S,* Sobhani K.* Longitudinal cohort analysis of demographic and clinical characteristics associated with variations in antibody response to BNT162b2 vaccination among healthcare workers at an academic medical center. BMJ Open. 2022: In Press.

 

Plummer JT, Contreras D, Zhang W, Binek A, Zhang R, Dezem F, Chen SC, Davis BD, Sincuir Martinez J, Stotland A, Kreimer S, Makhoul E, Heneidi S, Eno C, Shin B, Berg AH, Cheng S, Jordan SC, Vail E, Van Eyk J, Morgan MA. USA SARS-CoV-2 Epsilon Variant: Though Highly Transmissible Has an Adjusted Muted Host T-Cell Response. Clin Infect Dis. 2022: In Press.

Xu AM, Li D, Ebinger JE, Mengesha E, Elyanow R, Gittelman RM, Chapman H, Joung S, Botwin GJ, Pozdnyakova V, Debbas P, Mujukian A, Prostko JC, Frias EC, Stewart JL, Horizon AA, Merin N, Sobhani K, Figueiredo JC, Cheng S, Kaplan IM, McGovern DPB, Merchant A, Melmed GY, Braun J. Differences in SARS-CoV-2 Vaccine Response Dynamics Between Class-I- and Class-II-Specific T-Cell Receptors in Inflammatory Bowel Disease. Front Immunol. 2022 Apr 8;13:880190. 

Ebinger JE,* Lan R,* Driver M, Sun N, Botting P, Park E, Davis T, Minissian MB, Coleman B, Riggs R, Roberts P, Cheng S. Seasonal COVID-19 surge related hospital volumes and case fatality rates. BMC Infectious Diseases. 2022: Epub ahead of print.

Li D, Debbas P, Cheng S, Braun J, McGovern DPB, Melmed GY. Post-vaccination symptoms after a third dose of mRNA SARS-CoV-2 vaccination in patients with inflammatory bowel disease. medRxiv [Preprint]. Dec 7, 2021.

Li D, Xu A, Mengesha E, Elyanow R, Gittelman RM, Chapman H, Prostko JC, Frias EC, Stewart JL, Pozdnyakova V, Debbas P, Mujukian A, Horizon AA, Merin N, Joung S, Botwin GJ, Sobhani K, Figueiredo JC, Cheng S, Kaplan IM, McGovern DPB, Merchant A, Melmed GY, Braun J. The T-cell clonal response to SARS-CoV-2 vaccination in inflammatory bowel disease patients is augmented by anti-TNF therapy and often deficient in antibody-responders. medRxiv [Preprint]. PMID: 34909785.

Martino C, Kellman BP, Sandoval DR, Clausen TM, Marotz CA, Song SJ, Wandro S, Zaramela LS, Salido Benítez RA, Zhu Q, Armingol E, Vázquez-Baeza Y, McDonald D, Sorrentino JT, Taylor B, Belda-Ferre P, Liang C, Zhang Y, Schifanella L, Klatt NR, Havulinna AS, Jousilahti P, Huang S, Haiminen N, Parida L, Kim HC, Swafford AD, Zengler K, Cheng S, Inouye M, Niiranen T, Jain M, Salomaa V, Esko JD, Lewis NE, Knight R. Bacterial modification of the host glycosaminoglycan heparan sulfate modulates SARS-CoV-2 infectivity. bioRxiv [Preprint]. 2020 Aug 18:2020.

Cheng MH, Krieger JM, Kaynak B, Arditi M, Bahar I. Impact of South African 501.V2 Variant on SARS-CoV-2 Spike Infectivity and Neutralization: A Structure-based Computational Assessment. bioRxiv [Preprint]. 2021. January 11:2021.

Published Scientific Reports

Liu Y, Ebinger JE, Mostafa R, Budde P, Gajewski J, Walker B, Joung S, Wu M, Bräutigam M, Hesping F, Rupieper E, Schubert AS, Zucht HD, Braun J, Melmed GY, Sobhani K, Arditi M, Van Eyk JE,* Cheng S,* Fert-Bober J.* Paradoxical sex-specific patterns of autoantibody response to SARS-CoV-2 infection. J Transl Med. 2021 Dec 30;19(1):524 HIGH ALTMETRICS 

 

Ebinger JE, Lan R, Sun N, Wu M, Joung S, Botwin GJ, Botting P, Al-Amili D, Aronow H, Beekley J, Coleman B, Contreras S, Cozen W, Davis J, Debbas P, Diaz J, Driver M, Fert-Bober J, Gu Q, Heath M, Herrera E, Hoang A, Hussain SK, Huynh C, Kim L, Kittleson M, Liu Y, Lloyd J, Luong E, Malladi B, Merchant A, Merin N, Mujukian A, Nguyen N, Nguyen T, Pozdnyakova V, Rashid M, Raedschelders K, Reckamp KL, Rhoades K, Sternbach S, Vallejo R, White S, Tompkins R, Wong M, Arditi M, Figueiredo JC, Van Eyk JE, Miles PB, Chavira C, Shane R, Sobhani K, Melmed GY, McGovern DPB, Braun JG, Cheng S*, Minissian MB.* Symptomology Following mRNA Vaccination Against SARS-CoV-2. Prev Med 2021: Epub ahead of print.

Melmed GY, Botwin GJ, Li D, Sobhani K, Prostko J, Figueiredo J, Cheng S, Braun J, McGovern DPB. Antibody Responses Following SARS-CoV-2 mRNA Vaccination in Adults with Inflammatory Bowel Disease. Annals of Internal Medicine. 2021: Epub ahead of print HIGH ALTMETRICS 

Jordan SC, Shin B, Gadsden TM, Chu M, Petrosyan A, Le CN, Zabner R, Oft J, Pedraza I, Cheng S, Vo A, Ammerman N, Plummer J, Ge S, Froch M, Berg A, Toyoda M, Zhang R. T cell immune responses to SARS-CoV-2 and variants of concern (Alpha and Delta) in infected and vaccinated individuals. Cell Mol Immunol. 2021; Epub ahead of print.

Yuan N, Botting PG, Elad Y, Miller SJ, Cheng S, Ebinger JE, Kittleson MM. Practice Patterns and Patient Outcomes After Widespread Adoption of Remote Heart Failure Care. Circ Heart Fail. 2021;14:e008573. Epub ahead of print.

Porritt RA, Binek A, Paschold L, Noval Rivas M, McArdle A, Yonker LM, Alter G, Chandnani HK, Lopez M, Fasano A, Van Eyk JE, Binder M, Arditi M. The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children. J Clin Invest. 2021; Epub ahead of print HIGH ALTMETRICS 

Pozdnyakova V, Botwin GJ, Sobhani K, Prostko P, Braun J, Melmed GY, CORALE-IBD study group. Decreased Antibody Responses to Ad26.COV2.S Relative to SARS-CoV-2 mRNA Vaccines in Patients with Inflammatory Bowel Disease. Gastroenterology. 2021; Epub ahead of print.

Xian H, Liu Y, Rundberg Nilsson A, Gatchalian R, Crother TR, Tourtellotte WG, Zhang Y, Aleman-Muench GR, Lewis G, Chen W, Kang S, Luevanos M, Trudler D, Lipton SA, Soroosh P, Teijaro J, de la Torre JC, Arditi M, Karin M, Sanchez-Lopez E. Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation. Immunity. 2021: Epub ahead of print

 HIGH ALTMETRICS 

 

Kim H, Rebholz CM, Hegde S, LaFiura C, Raghavan M, Lloyd JF, Cheng S, Seidelmann SB. Plant-based diets, pescatarian diets and Covid-19 severity: a population-based case-control study in six countries. BMJ Nutr Prev Health. 2021; Epub ahead of print HIGH ALTMETRICS 

Ebinger J, Wells M, Ouyang D, Davis T, Kaufman N, Cheng S, Chugh S. A machine learning algorithm predicts duration of hospitalization in COVID-19 patients. Intell Based Med. 2021; Epub ahead of print.

Botwin GJ, Li D, Figueiredo J, Cheng S, Braun J, McGovern DPB, Melmed GY. Adverse Events Following SARS-CoV-2 mRNA Vaccination Among Patients with Inflammatory Bowel Disease. Am J Gastroenterol. 2021; Epub ahead of print.  HIGH ALTMETRICS 

Cheng MH, Porritt RA, Noval Rivas M, Krieger JM, Ozdemir AB, Garcia Jr G, Arumugaswami V, Fries BC, Arditi M, Bahar I. A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro. Structure. 2021; Epub ahead of print.

Yuan N, Pevnick JM, Botting PG, Elad Y, Miller SJ, Cheng S, Ebinger JE. Patient utilization and clinical practice patterns of remote cardiology clinic visits in the era of COVID-19. JAMA Netw Open. 2021; Epub ahead of print.  HIGH ALTMETRICS 

Ebinger JE, Fert-Bober J, Printsev I, Wu M, Sun N, Prostko JC, Frias EC, Stewart JL, Van Eyk JE, Braun JG,* Cheng S,* Sobhani K.* Antibody responses to the BNT162b2 mRNA vaccine in individuals previously infected with SARS-CoV-2. Nat Med. 2021. Epub ahead of print. PMID: 33795870 HIGH ALTMETRICS 
 

Porritt RA, Paschold L, Noval Rivas M, Cheng MH, Yonker LM, Chandnani H, Lopez M, Simnica D, Schultheiß C, Santiskulvong C, van Eyk J, McCormick JK, Fasano A, Bahar I, Binder M, Arditi M. HLA class I-associated expansion of TRBV11-2 T cells in Multisystem Inflammatory Syndrome in Children. J Clin Invest. 2021. Epub ahead of print. PMID: 33705359.  HIGH ALTMETRICS 

Ebinger J, Driver M, Ji H, Claggett B, Wu M, Luong E, Sun N, Botting P, Kim EH, Hoang A, Nguyen TT, Diaz J, Park E, Davis T, Hussain S, Cheng S,* Figueiredo JC.* Temporal variations in the severity of COVID-19 illness by race and ethnicity. BMJ Nutr Prev Health. 2021; Epub ahead of print.

Kennedy NA, Goodhand JR, Bewshea C, Nice R, Chee D, Lin S, Chanchlani N, Butterworth J, Cooney R, Croft NM, Hart AL, Irving PM, Kok KB, Lamb CA, Limdi JK, Macdonald J, McGovern DP, Mehta SJ, Murray CD, Patel KV, Pollok RC, Raine T, Russell RK, Selinger CP, Smith PJ, Bowden J, McDonald TJ, Lees CW, Sebastian S, Powell N, Ahmad T; Contributors to the CLARITY IBD study. Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab. Gut. 2021;70(5):865-875. PMID: 33753421; PMCID: PMC7992387.  HIGH ALTMETRICS 

Yuan N, Ji H, Sun N, Botting P, Nguyen T, Torbati S, Cheng S, Ebinger J. Pseudo-safety in a cohort of patients with COVID-19 discharged home from the emergency department. Emerg Med J. 2021. Epub ahead of print. PMID: 33602725.

Siegel CA, Melmed GY, McGovern DP, Rai V, Krammer F, Rubin DT, Abreu MT, Dubinsky MC; International Organization for the Study of Inflammatory Bowel Disease (IOIBD); International Organization for the Study of Inflammatory Bowel Diseases (IOIBD). SARS-CoV-2 vaccination for patients with inflammatory bowel diseases: recommendations from an international consensus meeting. Gut. 2021;70(4):635-640. PMID: 33472895; PMCID: PMC7818789.

Kim H, Hegde S, LaFiura C, Raghavan M, Luong E, Cheng S, Rebholz CM, Seidelmann SB. COVID-19 illness in relation to sleep and burnout. BMJ Nutr Prev Health. 2021. Epub ahead of print. PMCID: PMC7995669.
 

Ebinger JE, Botwin GJ, Albert CM, Alotaibi M, Arditi M, Berg AH, Binek A, Botting P, Fert-Bober J, Figueiredo JC, Grein JD, Hasan W, Henglin M, Hussain SK, Jain M, Joung S, Karin M, Kim EH, Li D, Liu Y, Luong E, McGovern DPB, Merchant A, Merin N, Miles PB, Minissian M, Nguyen TT, Raedschelders K, Rashid MA, Riera CE, Riggs RV, Sharma S, Sternbach S, Sun N, Tourtellotte WG, Van Eyk JE, Sobhani K,* Braun JG,* Cheng S.* Seroprevalence of antibodies to SARS-CoV-2 in healthcare workers: a cross-sectional study. BMJ Open. 2021;11(2):e043584. PMID: 33579769; PMCID: PMC7883610.
 

Shmueli H, Shah M, Ebinger JE, Nguyen LC, Chernomordik F, Flint N, Botting P, Siegel RJ. Left ventricular global longitudinal strain in identifying subclinical myocardial dysfunction among patients hospitalized with COVID-19. Int J Cardiol Heart Vasc. 2021;32:100719. PMID: 33521240; PMCID: PMC7830223.
 

Kim H, Hegde S, LaFiura C, Raghavan M, Sun N, Cheng S, Rebholz CM, Seidelmann SB. Access to personal protective equipment in exposed healthcare workers and COVID-19 illness, severity, symptoms and duration: a population-based case- control study in six countries. BMJ Glob Health. 2021;6(1):e004611. PMID: 33509841; PMCID: PMC7844929.
 

Rivas MN, Ebinger JE, Wu M, Sun N, Braun J, Sobhani K, Van Eyk JE, Cheng S,* Arditi M.* BCG vaccination history associates with decreased SARS-CoV-2 seroprevalence across a diverse cohort of health care workers. J Clin Invest. 2021;131(2):e145157. PMID: 33211672; PMCID: PMC7810479 HIGH ALTMETRICS 

Melmed GY, Rubin DT, McGovern DPB. Winter Is Coming! Clinical, Immunologic, and Practical Considerations for Vaccinating Patients With Inflammatory Bowel Disease During the Coronavirus Disease-2019 Pandemic. Gastroenterology. 2021;160(3):639-644. PMID: 33065064; PMCID: PMC7553998.

 

Potdar AA, Dube S, Naito T, Li K, Botwin G, Haritunians T, Li D, Casero D, Yang S, Bilsborough J, Perrigoue JG, Denson LA, Daly M, Targan SR, Fleshner P, Braun J, Kugathasan S, Stappenbeck TS, McGovern DPB. Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease. Gastroenterology. 2021;160(3):809-822.e7. PMID: 33160965.

Noval Rivas M, Porritt RA, Cheng MH, Bahar I, Arditi M. COVID-19-associated multisystem inflammatory syndrome in children (MIS-C): A novel disease that mimics toxic shock syndrome-the superantigen hypothesis. J Allergy Clin Immunol. 2021;147:57-59. PMID: 33075409.

Rowley AH, Shulman ST, Arditi M. Immune pathogenesis of COVID-19-related multisystem inflammatory syndrome in children. J Clin Invest. 2020 Nov 2;130:5619-5621. PMID: 32870815.

Cheng MH, Zhang S, Porritt RA, Noval Rivas M, Paschold L, Willscher E, Binder M, Arditi M, Bahar I. Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25254-25262. PMID: 32989130.

Goodman-Meza D, Rudas A, Chiang JN, Adamson PC, Ebinger J, Sun N, Botting P, Fulcher JA, Saab FG, Brook R, Eskin E, An U, Kordi M, Jew B, Balliu B, Chen Z, Hill BL, Rahmani E, Halperin E, Manuel V. A machine learning algorithm to increase COVID-19 inpatient diagnostic capacity. PLoS One. 2020 Sep 22;15(9):e0239474. PMID: 32960917; PMCID: PMC7508387.

Minissian MB, Ballard-Hernandez J, Coleman B, Chavez J, Sheffield L, Joung S, Parker A, Stepien SJ, Romero J, Floríndez LI, Simons CD, De Jesus M, Marshall D. Multi-Specialty Nursing During COVID-19: Lessons Learned in Southern California. Nurse Lead. 2020 Sep 7. Epub ahead of print. PMID: 32922217.

Rubin DT, Abreu MT, Rai V, Siegel CA; International Organization for the Study of Inflammatory Bowel Disease. Management of Patients With Crohn's Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting. Gastroenterology. 2020 Jul;159(1):6-13.e6. Epub 2020 Apr 6. PMID: 32272113; PMCID: PMC7194599.

Barsky LL, Ebinger JE, Alotaibi M, Jain M, Torbati S, Rosen BT, Cheng S. Efficacy of clinical evaluations for COVID-19 on the front line. Int J Emerg Med. 2020;13(1):54. PMID: 33160316; PMCID: PMC7647876.
 

Ebinger JE, Achamallah N, Ji H, Claggett BL, Sun N, Botting P, Nguyen TT, Luong E, Kim EH, Park E, Liu Y, Rosenberry R, Matusov Y, Zhao S, Pedraza I, Zaman T, Thompson M, Raedschelders K, Berg AH, Grein JD, Noble PW, Chugh SS, Bairey Merz CN, Marbán E, Van Eyk JE, Solomon SD, Albert CM, Chen P,* Cheng S.* Pre-existing traits associated with Covid-19 illness severity. PLoS One. 2020;15(7):e0236240. PMID: 32702044; PMCID: PMC7377468.
 

Lopez JJ, Ebinger JE, Allen S, Yildiz M, Henry TD. Adapting STEMI care for the COVID-19 pandemic: The case for low-risk STEMI triage and early discharge. Catheter Cardiovasc Interv. 2020:10.1002/ccd.28993. Epub ahead of print. PMID: 32478957; PMCID: PMC7300822.
 

Ebinger JE, Shah PK. Declining Admissions for Acute Cardiovascular Illness: The COVID-19 Paradox. J Am Coll Cardiol. 2020;76(3):289-291. Epub 2020 May 26. PMID: 32470513; PMCID: PMC7250547.
 

Ramireddy A, Chugh H, Reinier K, Ebinger J, Park E, Thompson M, Cingolani E, Cheng S, Marban E, Albert CM, Chugh SS. Experience With Hydroxychloroquine and Azithromycin in the Coronavirus Disease 2019 Pandemic: Implications for QT Interval Monitoring. J Am Heart Assoc. 2020;9(12):e017144. Epub 2020 May 28. PMID: 32463348; PMCID: PMC7429030.